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Year Number of Results
1892 1
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1965 6
1966 3
1967 5
1968 7
1969 5
1970 5
1971 5
1972 8
1973 13
1974 5
1975 27
1976 37
1977 41
1978 36
1979 51
1980 44
1981 59
1982 45
1983 62
1984 71
1985 60
1986 99
1987 234
1988 331
1989 377
1990 430
1991 364
1992 420
1993 418
1994 511
1995 483
1996 510
1997 553
1998 611
1999 738
2000 908
2001 1023
2002 1077
2003 1167
2004 1254
2005 1490
2006 1720
2007 1689
2008 1888
2009 2076
2010 2221
2011 2570
2012 2854
2013 2723
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2015 3441
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2017 3224
2018 4091
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2020 4900
2021 5266
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2023 5192
2024 1935

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68,420 results

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Page 1
Nucleoid-Associated Protein HU: A Lilliputian in Gene Regulation of Bacterial Virulence.
Stojkova P, Spidlova P, Stulik J. Stojkova P, et al. Front Cell Infect Microbiol. 2019 May 10;9:159. doi: 10.3389/fcimb.2019.00159. eCollection 2019. Front Cell Infect Microbiol. 2019. PMID: 31134164 Free PMC article. Review.
These transcription regulators are responsible for many important cellular processes and also are involved in pathogenesis of bacteria. The best-known nucleoid-associated proteins, such as HU, FIS, H-NS, and IHF, are often discussed. The most important findings in r …
These transcription regulators are responsible for many important cellular processes and also are involved in pathogenesis of bacteria. The …
HU: promoting or counteracting DNA compaction?
Dame RT, Goosen N. Dame RT, et al. FEBS Lett. 2002 Oct 9;529(2-3):151-6. doi: 10.1016/s0014-5793(02)03363-x. FEBS Lett. 2002. PMID: 12372591 Free article. Review.
The role of HU in Escherichia coli as both a protein involved in DNA compaction and as a protein with regulatory function seems to be firmly established. ...However, almost 30 years after its discovery, convincing evidence for the proposed role of HU in DNA compacti …
The role of HU in Escherichia coli as both a protein involved in DNA compaction and as a protein with regulatory function seems to be …
Biological sex divergence in transcriptomic profiles during the onset of hindlimb unloading-induced atrophy.
Tsitkanou S, Morena da Silva F, Cabrera AR, Schrems ER, Murach KA, Washington TA, Rosa-Caldwell ME, Greene NP. Tsitkanou S, et al. Am J Physiol Cell Physiol. 2023 Nov 1;325(5):C1276-C1293. doi: 10.1152/ajpcell.00352.2023. Epub 2023 Sep 25. Am J Physiol Cell Physiol. 2023. PMID: 37746697
Females exhibited muscle loss as early as 24 h of HU, whereas males after 168 h of HU. In males, pathways related to proteasome degradation were upregulated throughout 168 h of HU, whereas in females these pathways were upregulated up to …
Females exhibited muscle loss as early as 24 h of HU, whereas males after 168 h of HU. In males, pathways relate …
Effect of HU protein on the conformation and compaction of DNA in a nanochannel.
Guttula D, Liu F, van Kan JA, Arluison V, van der Maarel JRC. Guttula D, et al. Soft Matter. 2018 Mar 28;14(12):2322-2328. doi: 10.1039/c7sm02118f. Epub 2018 Feb 19. Soft Matter. 2018. PMID: 29457176
Pre-incubated DNA molecules contract in the longitudinal direction of the channel with increasing concentration of HU. This contraction is mainly due to HU-mediated bridging of distal DNA segments and is controlled by channel diameter as well as ionic composition an …
Pre-incubated DNA molecules contract in the longitudinal direction of the channel with increasing concentration of HU. This contracti …
Interaction of the Escherichia coli HU Protein with Various Topological Forms of DNA.
Huang L, Zhang Z, McMacken R. Huang L, et al. Biomolecules. 2021 Nov 19;11(11):1724. doi: 10.3390/biom11111724. Biomolecules. 2021. PMID: 34827722 Free PMC article.
Using radiolabeled HU, we examine the effects of DNA supercoiling on HU-DNA interactions. ...This binding preference, however, becomes negligible at HU/DNA mass ratios higher than 1:2. At saturation, HU binds both negatively supercoiled and relaxed DNA …
Using radiolabeled HU, we examine the effects of DNA supercoiling on HU-DNA interactions. ...This binding preference, however, …
Hindlimb unloading: rodent analog for microgravity.
Globus RK, Morey-Holton E. Globus RK, et al. J Appl Physiol (1985). 2016 May 15;120(10):1196-206. doi: 10.1152/japplphysiol.00997.2015. Epub 2016 Feb 11. J Appl Physiol (1985). 2016. PMID: 26869711 Free article. Review.
Indeed, results from early spaceflight and HU experiments confirmed the expected sensitivity of the musculoskeletal system to gravity loading. ...Analysis of the validity of the HU model is important given its potential value for both hypothesis testing and counterm …
Indeed, results from early spaceflight and HU experiments confirmed the expected sensitivity of the musculoskeletal system to gravity …
Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria.
Dorman CJ, Hinton JC, Free A. Dorman CJ, et al. Trends Microbiol. 1999 Mar;7(3):124-8. doi: 10.1016/s0966-842x(99)01455-9. Trends Microbiol. 1999. PMID: 10203842 Review.
The bacterial nucleoid-associated proteins H-NS and StpA can form homomeric or heteromeric complexes, a parallel with protein HU. Thus, functional modulation of H-NS and StpA by one another and by other proteins with appropriate interaction domains is possibl …
The bacterial nucleoid-associated proteins H-NS and StpA can form homomeric or heteromeric complexes, a parallel with protein HU
68,420 results
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